摘要 |
Provided herein are compositions and methods for forming adipose tissue. One aspect provides a method including contacting adipose progenitor cells and an agent for modulating HOX antisense intergenic RNA ("HOTAIR"), an adipose-derived exosome, a miRNA associated with an adipose-derived exosome, or a demethylation agent. Such contact can induce or increase adipogenesis, formation of white adipose, formation brown adipose, or transition of white adipose to brown adipose. |