发明名称 MODULATION OF HOTAIR AND ADIPOGENESIS
摘要 Provided herein are compositions and methods for forming adipose tissue. One aspect provides a method including contacting adipose progenitor cells and an agent for modulating HOX antisense intergenic RNA ("HOTAIR"), an adipose-derived exosome, a miRNA associated with an adipose-derived exosome, or a demethylation agent. Such contact can induce or increase adipogenesis, formation of white adipose, formation brown adipose, or transition of white adipose to brown adipose.
申请公布号 WO2015153880(A2) 申请公布日期 2015.10.08
申请号 WO2015US24079 申请日期 2015.04.02
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 MAO, JEREMY J.;YANG, GUODONG
分类号 A61K48/00;C12N15/85 主分类号 A61K48/00
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