发明名称 |
AMORPHOUS SOLID DISPERSION COMPRISING TAXANE, TABLET COMPRISING THE SAME, AND METHOD FOR PREPARING THE SAME |
摘要 |
The present invention provides an amorphous solid dispersion comprising a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present invention also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient. |
申请公布号 |
CA2944438(A1) |
申请公布日期 |
2015.10.08 |
申请号 |
CA20152944438 |
申请日期 |
2015.03.20 |
申请人 |
HANMI PHARM. CO., LTD. |
发明人 |
SRINIVASAN, SHANMUGAM;IM, HO TAEK;YOON, YOUNG SU;KIM, YONG IL;PARK, JAE HYUN;WOO, JONG SOO |
分类号 |
A61K9/20;A61K9/30;A61K31/335;A61K31/337 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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