发明名称 Oxindole derivatives
摘要 The invention describes compounds of the general formula I or the pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are herein described, a process for their manufacture, medicaments containing them as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as antiproliferative agents and may be especially useful for the treatment of cancer.
申请公布号 US7576082(B2) 申请公布日期 2009.08.18
申请号 US20060471363 申请日期 2006.06.20
申请人 HOFFMAN-LA ROCHE INC. 发明人 LUK KIN-CHUN;SO SUNG-SAU;ZHANG JING;ZHANG ZHUMING
分类号 A61K31/535;A61K31/40;A61K31/415;A61K31/445;C07D209/04;C07D401/00;C07D403/02;C07D413/00;C07D487/00 主分类号 A61K31/535
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