发明名称 METHOD AND MEDICINE FOR INHIBITING EXPRESSION OF SPECIFIC GENE
摘要 <P>PROBLEM TO BE SOLVED: To provide a medicine containing at least one double-stranded oligoribonucleotide (double-stranded RNA) designed to inhibit the expression of a target gene. <P>SOLUTION: One strand of the double-stranded RNA is at least partially complementary to a targeted gene. The targeted gene can be selected from the following group: cancer genes, cytokine genes, Id protein genes, developmental genes, and prion genes. The target gene can be expressed in a pathogenic organisms (especially Plasmodium). The targeted gene can preferably also be a part of viruses or viroids which are pathogenic to humans. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013074901(A) 申请公布日期 2013.04.25
申请号 JP20130006076 申请日期 2013.01.17
申请人 ALNYLAM EUROPE AG 发明人 KREUTZER ROLAND;LIMMER STEPHAN
分类号 C12N15/09;C12N15/113;A61K9/127;A61K31/70;A61K31/713;A61K35/76;A61K38/00;A61K47/48;A61K48/00;A61P25/28;A61P31/12;A61P35/00;C12N15/11 主分类号 C12N15/09
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