发明名称 |
NOVEL HISTONE DEACETYLASE INHIBITORS AND THEIR USE IN THERAPY |
摘要 |
A compound of the formula: (I) or a pharmaceutically acceptable salt thereof, wherein: L is a 5-membered nitrogen-containing heteroaryl which is optionally fused to a benzene; Y is a 5, 6 or 7-membered nitrogen-containing heteroaryl, which is optionally fused to a benzene; and W is a zinc-binding group. The compounds are HDAC inhibitors and therefore have potential utility in therapy. |
申请公布号 |
EP2917202(A1) |
申请公布日期 |
2015.09.16 |
申请号 |
EP20130792060 |
申请日期 |
2013.11.06 |
申请人 |
KARUS THERAPEUTICS LIMITED |
发明人 |
SHUTTLEWORTH, STEPHEN JOSEPH;TOMASSI, CYRILLE DAVY;CECIL, ALEXANDER RICHARD LIAM;MACCORMICK, SOMHAIRLE;NODES, WILLIAM JOHN;SILVA, FRANCK ALEXANDRE |
分类号 |
C07D401/12;A61K31/4439;A61P7/00;A61P9/00;A61P29/00;A61P35/00 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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