Methods and Kits for Measuring Von Willebrand Factor

摘要

Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Ibα having at least two of a G233V, D235Y and M239V mutations and an agent to detect a complex between the recombinant glycoprotein Ibα and von Willebrand factor.

主权项

1. An isolated GPIbα polypeptide that is SEQ ID NO:11 with at least one mutation that is D235Y.