| 发明名称 |
COLCHICINE FORMULATIONS; METHODS OF MAKING; AND METHODS OF USE THEREOF |
| 摘要 |
Disclosed are new photostable colchicine formulations, methods of preparing the formulations, and uses thereof. |
| 申请公布号 |
US2015164831(A1) |
申请公布日期 |
2015.06.18 |
| 申请号 |
US201314389523 |
申请日期 |
2013.03.29 |
| 申请人 |
TAKEDA PHARMACEUTICALS U.S.A., INC. |
发明人 |
Roberts Richard H.;Erkoboni David;Kraut Bela;Kudsi Maher;Naringrekar Gandha V. |
| 分类号 |
A61K31/165;A61K9/20;A61K9/16 |
主分类号 |
A61K31/165 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A colchicine dosage form, comprising:
colchicine, a pharmaceutically acceptable excipient, and a light protecting agent selected from a light blocking material, a light absorbing material, or a light blocking material and a light absorbing material; wherein the dosage form can be administered as a sprinkle formulation, wherein the sprinkle formulation does not contain more than 0.06% beta-lumicolchicine and gamma-lumicolchicine combined weight after exposure to 1500 to 3000 lux for 15 minutes (about 2700K or about 6500K color temperature). |
| 地址 |
Deerfield IL US |
