Methods and compositions involving (S)-bucindolol

摘要

Disclosed is bucindolol substantially free of its R-stereoisomer. Also disclosed are pharmaceutical compositions that include bucindolol substantially free of its R-stereoisomer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Also disclosed are methods of treating a patient that involve administering to the patient a therapeutically effective amount of a composition of the present invention. Formula (I).;

主权项

1. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and bucindolol substantially free of its R-stereoisomer and an additional pharmaceutical agent, wherein the additional pharmaceutical agent is a nitric oxide (NO) enhancing agent.