TUNNELING JUNCTION TO DISTINGUISH TARGETED DNA SEGMENT

摘要

A nanodevice includes a nanochannel disposed through a dielectric material. A first electrode is disposed on a first side of the nanochannel, is formed within the dielectric material and has a surface exposed within the nanochannel. A second electrode is disposed on a second side of the nanochannel, is formed within the dielectric material and has a surface exposed within the nanochannel opposite the first electrode. A power circuit is connected between the first and second electrodes to create a potential difference between the first and second electrodes such that portions of a molecule can be identified by a change in electrical properties across the first and second electrodes as the molecule passes.

主权项

1. A method for analyzing a molecule, comprising:
providing a nanochannel disposed through a dielectric material, a first electrode formed within the dielectric material and having a surface exposed within the nanochannel, and a second electrode formed within the dielectric material and having a surface exposed within the nanochannel and a power circuit connected between the first and second electrodes to create a potential difference between the first and second electrodes such that portions of a molecule can be identified by a change in electrical properties across the first and second electrodes; feeding a linearized version of the molecule down the nanochannel such that the molecule passes between the first and second electrodes; and measuring the change in electrical properties across the first and second electrodes as the molecule is disposed between the first and second electrodes to characterize the molecule or portions thereof.