COMPOSITIONS AND METHODS FOR USING PLATELET-RICH PLASMA FOR DRUG DISCOVERY, CELL NUCLEAR REPROGRAMMING, PROLIFERATION OR DIFFERENTIATION

摘要

Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions, and the use of compositions containing platelet-rich plasma to accelerate or complete the differentiation of a cell line. Particularly, use of platelet-rich plasma in conjunction with cell differentiation.

主权项

1. A method of producing induced pluripotent stem (iPS) cells comprising:
obtaining fibroblast cells from skin tissue from an individual, administering a growth factor selected from the group consisting of vascular endothelial growth factor (VEGF), granulocyte colony stimulating factor (G-CSF), plerixafor, sargramostim, γ-tocotrienol, vitamin E, ancestim and bone morphogenic growth factor to the individual, isolating platelet-rich plasma (PRP) from whole blood of the individual, and treating the fibroblast cells of the individual with the isolated PRP.