发明名称 |
HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE |
摘要 |
The present invention relates to heterocyclic compounds useful for antagonizing angiotensin II Type 2 (AT2) receptor. More particularly the invention relates to piperazine and diazepine compounds, compositions containing them and their use in methods of treating or preventing disorders or diseases associated with AT2 receptor function including neuropathic pain, inflammatory pain, conditions associated with neuronal hypersensitivity, impaired nerve conduction velocity, cell proliferation disorders, disorders associated with an imbalance between bone resorption and bone formation and disorders associated with aberrant nerve regeneration. |
申请公布号 |
EP2807153(A1) |
申请公布日期 |
2014.12.03 |
申请号 |
EP20130741446 |
申请日期 |
2013.01.25 |
申请人 |
SPINIFEX PHARMACEUTICALS PTY LTD |
发明人 |
MCCARTHY, THOMAS DAVID;NAYLOR, ALAN |
分类号 |
C07D241/04;A61K31/496;A61K31/4985;A61K31/551;A61P25/02;A61P25/04;A61P35/00;C07D243/08;C07D403/04;C07D413/04;C07D413/06;C07D487/04 |
主分类号 |
C07D241/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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