发明名称 IRON-BASED MONTMORILLONITE MEDICAMENT FOR TREATING HYPERPHOSPHATEMIA AND IRON-DEFICIENCY ANEMIA, AND PREPARATION METHOD THEREFOR
摘要 The present invention relates to an iron-based montmorillonite medicament for treating hyperphosphatemia and iron-deficiency anemia, and a preparation method therefor. The medicament comprises an effective ingredient iron-based montmorillonite, and the iron-based montmorillonite (Fe-montmorillonite) is obtained by soaking or eluting medicinal montmorillonite by using a water soluble iron salt solution. A preparation prepared by using the effective ingredient and adding a pharmaceutical excipient or prepared by using the effective ingredient and not adding the pharmaceutical excipient is administrated through a gastrointestinal tract, and the effective ingredient and phosphate in a digestive tract of a patient are combined into an insoluble substance and the insoluble substance is discharged from the body through the digestive tract, so as to reduce phosphate in the body of the patient suffering from chronic renal failure, thereby achieving the objective of treating hyperphosphatemia. In addition, the iron-based montmorillonite dissociates iron ions uncombined with phosphate, the iron ions are absorbed by a human body, and iron ions in the human body are supplemented, thereby achieving the objective of treating iron-deficiency anemia of the patient suffering from the chronic renal failure. The medicament can also be used as a preventive for preventing hyperphosphatemia and iron-deficiency anemia of the patient suffering from the chronic renal failure.
申请公布号 WO2014183347(A1) 申请公布日期 2014.11.20
申请号 WO2013CN81557 申请日期 2013.08.15
申请人 QIAO, MIN;SHANDONG SIBANGDE PHARMACEUTICAL CO., LTD. 发明人 QIAO, MIN;YANG, YIJUAN;LIU, GANG
分类号 A61K33/26;A61K9/14;A61K35/02;A61P7/08 主分类号 A61K33/26
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