发明名称 |
Induction of tumor immunity by variants of folate binding protein |
摘要 |
The present invention is directed to variants of antigens comprising folate binding protein epitope (E39) as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness. |
申请公布号 |
SI2371854(T1) |
申请公布日期 |
2014.09.30 |
申请号 |
SI20020031046T |
申请日期 |
2002.03.08 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM OFFICE OF THE GENERAL COUNSEL;THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. |
发明人 |
IOANNIDES CONSTANTIN G.;PEOPLES GEORGE E. |
分类号 |
A61K9/12;A61K9/72;A61K39/00;A61P35/00;C07K7/06;C07K14/47;C07K14/82 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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