发明名称 NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES AS ALDOSTERONE SYNTHASE (CYP11B2 OR CYP11B1) INHIBITORS
摘要 The invention provides novel compounds having the general formula (1) wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, R11 and A are as described herein, compositions including the compounds and methods of using the compounds. The compounds of formula (I) are useful as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment of various disorders.
申请公布号 CA2897417(A1) 申请公布日期 2014.09.12
申请号 CA20142897417 申请日期 2014.03.05
申请人 F. HOFFMANN-LA ROCHE AG 发明人 AEBI, JOHANNES;AMREIN, KURT;HORNSPERGER, BENOIT;KUHN, BERND;MAERKI, HANS P.;MAYWEG, ALEXANDER V.;TAN, XUEFEI
分类号 C07D401/14;A61K31/4709;A61K31/506;A61P5/40;A61P9/04;A61P9/12;A61P13/12;C07D401/10 主分类号 C07D401/14
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