发明名称 Peptide-modified polyurethane compositions and associated methods
摘要 Peptide-modified polyurethanes comprising the reaction product of an isocyanate, a chain extender, and a peptide are provided. Also provided processes for making a peptide-modified polyurethane comprising: providing an isocyanate; providing a chain extender; providing a peptide; and allowing the isocyanate, chain extender, and peptide to react thereby forming the peptide-modified polyurethane, as well as methods for treating a subject comprising: providing a peptide-modified polyurethane that comprises the reaction product of an isocyanate, a chain extender, and a peptide; and administering the peptide-modified polyurethane to the subject.
申请公布号 US8791073(B2) 申请公布日期 2014.07.29
申请号 US200511129941 申请日期 2005.05.16
申请人 William Marsh Rice University 发明人 West Jennifer L.;Jun Ho-Wook;Taite Lakeshia J.
分类号 A61K38/00;C07K7/06;C08G18/10;C08L75/04;A61K38/17;C08G18/08;C08G18/64;A61K47/48 主分类号 A61K38/00
代理机构 Reed Smith LLP 代理人 Reed Smith LLP ;Riddle Robert R.
主权项 1. A peptide-modified polyurethane comprising a reaction product of an isocyanate, a chain extender, and a peptide, wherein the peptide is incorporated into and between units of a backbone chain of the peptide-modified polyurethane.
地址 Houston TX US