A new type of universal probes for the detection of genomic variants

摘要

The present invention relates to a composition comprising a first set of probes and a second set of probes, composed of one or more DNA nucleotide(s) and five or more LNA (locked nucleic acid) nucleotides, wherein the probes differ in one, two or three LNA random position(s) and the base at a discriminating position. Further, the present invention relates to a method of detecting genomic variants by means of the aforementioned probes. Moreover, the invention relates to a library of a plurality of probes.