发明名称 |
Acido (1R,6S)-2-azabiciclo[4.3.0]nonano-8,8-difosfónico y su uso en el tratamiento o la prevención de trastornos óseos, por ejemplo, osteoporosis o enfermedad de Paget |
摘要 |
Disclosed is a new composition of matter, substantially enantiomerically pure (1R,6S)-2-Azabicyclo-[4.3.0]nonane-8,8-diphosphonic acid, methods of preparing this new composition of matter, a pharmaceutical composition comprising the new composition, and administration of the composition in methods of treating bone disorders such as osteoporosis, osteolytic bone metastasis, rheumatoid arthritis and osteoarthritis. |
申请公布号 |
ES2472705(T3) |
申请公布日期 |
2014.07.02 |
申请号 |
ES20070862997T |
申请日期 |
2007.12.14 |
申请人 |
ISIS INNOVATION LIMITED;UNIVERSITY OF ROCHESTER;ISIS INNOVATION LIMITED;UNIVERSITY OF ROCHESTER |
发明人 |
EBETINO, FRANK HALLOCK;BOECKMAN, ROBERT KENNETH JR.;SONG, XINYI |
分类号 |
C07F9/576;A61K31/663;A61K31/675;A61P19/08;A61P19/10 |
主分类号 |
C07F9/576 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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