发明名称 |
Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
摘要 |
The present invention provides hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile. |
申请公布号 |
US8748401(B2) |
申请公布日期 |
2014.06.10 |
申请号 |
US201313917124 |
申请日期 |
2013.06.13 |
申请人 |
Incyte Corporation |
发明人 |
Rodgers James D.;Shilling Adam;Arvanitis Argyrios G.;Shepard Stacey;Galya Laurine G.;Li Mei;Nedza Frank M. |
分类号 |
A61K31/70;C07H17/02 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of Formula I:or a pharmaceutically acceptable salt thereof, wherein:
one C—H group is replaced with:or,
two C—H groups are each independently replaced with C—OH and one C—H group is replaced with: and pharmaceutically acceptable salts thereof.
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地址 |
Wilmington DE US |