| 摘要 |
<p>The invention relates to a method for producing carboxylic acid derivatives of general formula (1a): H-(C=0)-R (la), in which R is selected from the group comprising OR1 and NR2R3, wherein R1 is unsubstituted or at least monosubstituted C1-C15 alkyl, C5-C10 cycloalkyl, C5-C10 heterocyclyl, C5-C10 aryl, or C5-C10 heteroaryl, wherein the substituents are selected from the group comprising C1-C15 alkyl, C1-C6 alkoxy, C5-C10 cycloalkyl, and C5-C10 aryl; R2 and R3, independently of one another, are hydrogen or unsubstituted or at least monosubstituted C1-C15 alkyl, C5-C10 cycloalkyl, C5-C10 heterocyclyl, C5-C10 aryl, or C5-C10 heteroaryl, wherein the substituents are selected from the group comprising C1-C15 alkyl, C5-C10 cycloalkyl, and C5-C10 aryl, or R2 and R3 form a five- or six-membered ring together with the nitrogen atom, which ring optionally additionally contains one or more heteroatoms selected from O, S, and N, which heteroatom bears the substituent R4, wherein R4 is hydrogen or C1-C6 alkyl; by reacting a reaction mixture (Rg) containing carbon dioxide, hydrogen, and an alcohol of general formula (Ib): R1-OH (Ib), in which R1 has the aforementioned meanings, or an amine of general formula (Ic): NHR2R3 (Ic), in which R2 and R3, independently of each other, have the aforementioned meanings, in a hydrogenation reactor in the presence of a catalyst containing gold at a pressure in the range of 0.2 to 30 MPa and a temperature in the range of 20 to 200 °C.</p> |
