| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a novel sulphate of 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)benzamide, which can be used in treating diseases which respond to protein kinase inhibition. The sulphate is obtained by reacting 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)benzamide in form of a free base with sulphuric acid in a solvent medium.EFFECT: salt has low hygroscopicity and high solubility.2 cl, 8 dwg, 17 tbl, 11 ex |
