PIRROL[1,2-A] IMIDAZOLODIONA EFETIVA NO TRATAMENTO DE NEUROTOXICIDADE INDUZIDA POR AGENTES QUIMIOTERAPÊUTICOS

摘要

The use of a compound of formula (I) is disclosed in treating and/or preventing chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.