发明名称 |
Double-stranded polynucleotide |
摘要 |
Disclosed is a double-stranded polynucleotide which is stable against ribonucleases and has an RNA-silencing activity. Specifically disclosed is a double-stranded polynucleotide composed of a sense strand and an antisense strand. The double-stranded polynucleotide comprises a polynucleotide containing a nucleotide unit comprising an alternating combination of DNA and 2’-O-methyl RNA. |
申请公布号 |
AU2009267295(B2) |
申请公布日期 |
2013.09.26 |
申请号 |
AU20090267295 |
申请日期 |
2009.06.30 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
HIROTA, YASUHIDE;KOIZUMI, MAKOTO |
分类号 |
C12N15/113;A61K31/713;A61K48/00;A61P43/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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