TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS

摘要

Compositions of matter including (R)-2,5,6,8-tetramethyl-8-((3E,7E)-4,8,12- trimethyltrideca-3,7, 1 1 -trienyl)- 1,2,3,8,9, 10-hexahydrochromeno[5,6- e][l,3]oxazine and (R)-2,6,8-trimethyl-8-((3E,7E)-4,8,12-trimethyltrideca-3,7, 11- trienyl)-1,2,3,8,9, 10-hexahydrochromeno[5,6-e][1,3]oxazine are disclosed herein. Further disclosed are methods of preparation of such compounds and the use of such compounds as anticancer agents.