METHODS OF INHIBITING INFLAMMATION COMPRISING INHIBITING CD63

摘要

The invention relates to methods of inhibiting inflammation in a system comprising reducing or inhibiting CD63 in said system, wherein said inflammation is IgE-negative. The invention also relates to methods for inhibiting leukocyte recruitment in a system, inhibiting leukocyte rolling in a system, or inhibiting leukocyte extravasation in a system comprising reducing or inhibiting CD63 in said system. The invention also provides a method of reducing P-selectin levels comprising reducing or inhibiting CD63, and a method of reducing P-selectin clustering comprising reducing or inhibiting CD63.