| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide such a salt, having excellent characteristics in the respect of the stability and hygroscopicity and having a reproducible crystal structure, of 3-ä(2S, 4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazole-5-yl)piperazine-1-yl]pyrrolidine-2-ylcarbonyl}thiazolidine (compound I) that is useful as a dipeptidyl peptidase-IV inhibitor. <P>SOLUTION: There are provided salts of 3-ä(2S, 4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazole-5-yl) piperazine-1-yl]pyrrolidine-2-ylcarbonyl} thiazolidine and an organic or inorganic, monobasic through tribasic acid, or solvates thereof (except 2.5 hydrobromide of 3-ä(2S, 4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazole-5-yl)piperazine-1-yl]pyrrolidine-2-ylcarbonyl}thiazolidine, or a solvate thereof). <P>COPYRIGHT: (C)2013,JPO&INPIT |
