LYCOPENE INTERMEDIATE 1, 3, 6, 10-TETRA-DOUBLE BOND PENTADEC-PHOSPHONATE, PREPARATION METHOD AND APPLICATION THEREOF

摘要

The invention relates to a novel important lycopene intermediate 3, 7, 11-trimethyl-1, 3, 6, 10-tetraene-dodecyl diethyl phosphonate. A current lycopene intermediate 2, 4, 6, 10-tetra-double bond pentadec-carbon phosphonate is difficult to synthesize. The invention provides a novel intermediate, which has the following synthesis steps of: preparing 2, 6, 10-trimethyl-3, 5, 9-undecane triene-1-aldehyde from pseudoionone; preparing 2, 6, 10-trimethyl-2, 5, 9-undecane triene-1-aldehyde from the 2, 6, 10-trimethyl-3, 5, 9-undecane triene-1-aldehyde; and subjecting the 2, 6, 10-trimethyl-2, 5, 9-undecane triene-1-aldehyde and tetraethyl methylenediphosphonate to condensation reaction to obtain target product. The invention can generate novel intermediate from raw material pseudoionone only by four reactions, thus the reactions are easy to control and great industrial value are achieved.