| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention concerns pharmaceutics, particularly method of obtaining solid formulations containing vardenafil hydrochloride trihydrate. Method involves processing of formulation containing vardenafil hydrochloride or its hydrate (modification) by humid gas with relative humidity from 35 to 100% until vardenafil hydrochloride trihydrate is formed. In addition, invention concerns solid formulation of vardenafil hydrochloride trihydrate obtained by the claimed method. ^ EFFECT: improved stability of formulations obtained, obtaining solid formulations in unified replicable form. ^ 4 cl, 8 dwg, 8 tbl, 12 ex |
