发明名称 |
Metronomic convection enhanced delivery of intrathecal chemotherapy using an implanted magnetic breather pump (MBP) for leptomeningeal carcinomatosis |
摘要 |
A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. |
申请公布号 |
US8323269(B2) |
申请公布日期 |
2012.12.04 |
申请号 |
US20090581756 |
申请日期 |
2009.10.19 |
申请人 |
SHACHAR YEHOSHUA;CHEN THOMAS C.;FARKAS LESLIE;MARX BRUCE;JOHNSON DAVID;FARKAS LASZLO;PHARMACO-KINESIS CORPORATION |
发明人 |
SHACHAR YEHOSHUA;CHEN THOMAS C.;FARKAS LESLIE;MARX BRUCE;JOHNSON DAVID;FARKAS LASZLO |
分类号 |
A61F2/958;A61K9/22 |
主分类号 |
A61F2/958 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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