发明名称 |
HUMANIZED ANTI-AMYLOID-B OLIGOMER ANTIBODY |
摘要 |
<p>An anti-A² oligomer humanized antibody which does not bind to A² monomers and specifically binds only to A² oligomers; an anti-cognitive dysfunction agent, an agent for treating Alzheimer's disease, an agent for suppressing formation of neuritic plaque and an inhibitor of formation of A² amyloid fiber comprising the antibody as an active ingredient; a method for at least one of preventing and treating cognitive dysfunction or Alzheimer's disease, comprising the step of administering the antibody; and a method for suppressing progression of Alzheimer's disease, comprising the step of administering the antibody.</p> |
申请公布号 |
EP2463368(A9) |
申请公布日期 |
2012.11.28 |
申请号 |
EP20100806566 |
申请日期 |
2010.08.06 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
KUBOTA, TSUGUO;SUZUKI, NOBUYUKI |
分类号 |
C12N15/09;A61K39/395;A61P25/28;C07K16/18;C07K16/46 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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