| 发明名称 |
TREATMENT OF FILAGGRIN (FLG) RELATED DISEASES BY MODULATION OF FLG EXPRESSION AND ACTIVITY |
| 摘要 |
The present invention relates to antisense oligonucleotides and/or compounds that modulate the expression of and/or function of Filaggrin (FLG), in particular, by targeting natural antisense polynucleotides of Filaggrin (FLG). The invention also relates to the identification of these antisense oligonucleotides and/or compounds and their use in treating diseases and disorders associated with the expression of FLG.
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| 申请公布号 |
US2012295952(A1) |
申请公布日期 |
2012.11.22 |
| 申请号 |
US201013497454 |
申请日期 |
2010.09.24 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;COITO CARLOS;CURNA, INC. |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;COITO CARLOS |
| 分类号 |
A61K31/713;A61P1/00;A61P9/00;A61P11/06;A61P17/00;A61P17/06;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P37/00;A61P37/08;C12N5/071;C12N15/113;G01N25/04 |
主分类号 |
A61K31/713 |
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