发明名称 |
Nanoparticulate quinazoline derivative formulations |
摘要 |
The present invention is directed to nanoparticulate quinazoline derivative compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The nanoparticulate quinazoline derivative particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the treatment of hyperproliferative disorders, such as cancer and other neoplastic diseases. The compositions may include quinazolinamine derivatives such as erlotinib or a salt thereof. |
申请公布号 |
US8309133(B2) |
申请公布日期 |
2012.11.13 |
申请号 |
US20060402264 |
申请日期 |
2006.04.12 |
申请人 |
LIVERSIDGE GARY G.;JENKINS SCOTT;ALKERMES PHARMA IRELAND LIMITED |
发明人 |
LIVERSIDGE GARY G.;JENKINS SCOTT |
分类号 |
A61K9/20;A61K9/48 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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