摘要 |
<p>Compounds of formula (I) wherein Rx, Rz, R9, R10, R14, R14', R15, R15', A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.</p> |
申请人 |
ORION CORPORATION;TOERMAEKANGAS, OLLI;WOHLFAHRT, GERD;SALO, HARRI;RAMASUBRAMANIAN, RATHNA, DURGA;PATRA, PRANAB, KUMAR;MARTIN, ARPUTHARAJ, EBENEZER;HEIKKINEN, TERHI;VESALAINEN, ANNIINA;MOILANEN, ANU;KARJALAINEN, ARJA |
发明人 |
TOERMAEKANGAS, OLLI;WOHLFAHRT, GERD;SALO, HARRI;RAMASUBRAMANIAN, RATHNA, DURGA;PATRA, PRANAB, KUMAR;MARTIN, ARPUTHARAJ, EBENEZER;HEIKKINEN, TERHI;VESALAINEN, ANNIINA;MOILANEN, ANU;KARJALAINEN, ARJA |