发明名称 IMIDAZOPYRIDINE AND PURINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE.
摘要 <p>The invention provides compounds of Formulas Ia-Ib, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4, R5 and R16 are defined herein, a pharmaceutical composition that includes a compound of Formulas Ia-Ib and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of using the compound or composition in therapy., as an inhibitor of TYK2 kinase and conditions related, such as inflammatory illenesses, inflammatory bowel disease or psoriasis.</p>
申请公布号 MX2012010265(A) 申请公布日期 2012.10.01
申请号 MX20120010265 申请日期 2011.03.15
申请人 F. HOFFMANN-LA ROCHE AG.* 发明人 YINGJIE LAI;STEVEN R. MAGNUSON;JUN LIANG;BIRONG ZHANG;VICKIE H. TSUI;KIRK ROBARGE
分类号 A61K31/437;A61K31/4406;A61K31/4409;A61K31/444;A61K31/501;A61K31/506;A61K31/52;A61K31/5377;A61K31/541;A61P1/00;A61P17/06;A61P29/00;C07D471/04;C07D473/34;C07D491/107 主分类号 A61K31/437
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