发明名称 METHOD OF USING DIKETOPIPERAZINES AND COMPOSITION CONTAINING THEM
摘要 <P>PROBLEM TO BE SOLVED: To provide a method of treating a disease or condition mediated by a platelet activating factor (PAF), a method of inhibiting platelet aggregation, and a method of inhibiting the production and/or release of interleukin 8 (IL-8) by cells. <P>SOLUTION: The effects of PAF and the production and/or release of IL-8 are inhibited by a compound of formula (1), wherein R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>are defined in the application, or a physiologically-acceptable salt thereof and pharmaceutical compositions comprising these compounds. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012176980(A) 申请公布日期 2012.09.13
申请号 JP20120129131 申请日期 2012.06.06
申请人 DMI BIOSCIENCES INC 发明人 BAR-OR DAVID;CURTIS C GERALD;RAO NAGARAJA K R;THOMAS GREG
分类号 A61K38/00;A61K31/495;A61K31/496;A61P7/02;A61P7/04;A61P9/00;A61P11/00;A61P11/06;A61P21/00;A61P29/00;A61P31/00;A61P31/04;A61P31/16;A61P37/08;A61P43/00 主分类号 A61K38/00
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