摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of treating a disease or condition mediated by a platelet activating factor (PAF), a method of inhibiting platelet aggregation, and a method of inhibiting the production and/or release of interleukin 8 (IL-8) by cells. <P>SOLUTION: The effects of PAF and the production and/or release of IL-8 are inhibited by a compound of formula (1), wherein R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>are defined in the application, or a physiologically-acceptable salt thereof and pharmaceutical compositions comprising these compounds. <P>COPYRIGHT: (C)2012,JPO&INPIT |