| 发明名称 |
TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY |
| 摘要 |
<p>The present invention relates to tetrahydroisoquinoline of the formula (I)
or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GlyT1 inhibitors.</p> |
| 申请公布号 |
EP2271625(B1) |
申请公布日期 |
2012.09.12 |
| 申请号 |
EP20090727055 |
申请日期 |
2009.03.31 |
| 申请人 |
ABBOTT GMBH & CO. KG;ABBOTT LABORATORIES |
发明人 |
AMBERG, WILHELM;OCHSE, MICHAEL;LANGE, UDO;BRAJE, WILFRIED;BEHL, BERTHOLD;HORNBERGER, WILFRIED;MEZLER, MARIO;HUTCHINS, CHARLES W. |
| 分类号 |
C07D217/18;A61K31/472;A61P25/28;C07D401/06;C07D401/12;C07D409/14;C07D413/12;C07D417/12;C07D498/04;C07D513/04 |
主分类号 |
C07D217/18 |
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