NANOPARTICLES CONTAINING CYCLODEXTRIN AND BIOLOGICALLY ACTIVE MOLECULE, AND USING THEM

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents nanoparticles containing a biodegradable polymer, cyclodextrin or their derivative and a biologically active molecule wherein said biodegradable polymer is a polyvinylmethylether maleic anhydride (PVM/MA) copolymer; and said biologically active molecule is a substance representing a substrate of P-glycoprotein enzyme. ^ EFFECT: invention provides higher bioavailability of lipophilic oral drugs or those being the substrate of P-glycoprotein enzyme. ^ 9 cl, 7 ex, 9 tbl, 8 dwg