发明名称 |
(2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide |
摘要 |
The present invention related to the ±7-selective ligand (2S,3R)-N-(2-((3-pyridinyl)methyl)-l-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide or a pharmaceutical acceptable salt thereof and (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide or a pharmaceutical acceptable salt thereof, substantially free of (2R,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide or a pharmaceutical acceptable salt thereof, (2S,3S)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide or a pharmaceutical acceptable salt thereof and (2R,3S)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene -2-carboxamide or a pharmaceutical acceptable salt thereof. |
申请公布号 |
EP2484363(A1) |
申请公布日期 |
2012.08.08 |
申请号 |
EP20120164661 |
申请日期 |
2008.08.01 |
申请人 |
TARGACEPT, INC.;MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC |
发明人 |
MAZUROV,, ANATOLY A |
分类号 |
A61K31/4545;A61K45/06;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D453/02 |
主分类号 |
A61K31/4545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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