摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to veterinary virology and biotechnology. What is described is an emulsion inactivated associated vaccine for parvoviral, rheoviral, type I herpes-viral infections and a viral diarrhoeia - cattle mucosal disease (CMD). The vaccine contains a mixture of the concentrated antigen materials of Parvo 32459-DEP parvovirus strains of type I CMD, Reo I - Lang-DEP rheovirus strain of type I CMD, TK-A- (VIEV)-V2-DEP herpes-virus strain of type I CMD and NADL-DEP virus strain of viral diarrhoeia - cattle mucosal disease. The antigen material of the strains is inactivated by 1.2.-aminoethylaziridine. The concentrated and avirulent antigen materials are bound with an adjuvant in the effective relation. ^ EFFECT: vaccine induces a high level of antibodies to parvoviral, rheoviral, type I herpes-viral infections and viral diarrhoeia - cattle mucosal disease, provides reliable protection of a foetus, newborn calves, young growth of completion of growing and sagination, and also pregnant cows. ^ 4 cl, 5 tbl, 6 ex |