发明名称 |
MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF |
摘要 |
The present invention relates to multimeric (e.g., dimeric, trimeric) forms of peptide vectors that are capable of crossing the blood-brain barrier (BBB) or efficiently entering particular cell types. These multimeric peptide vectors, when conjugated to agents (e.g., therapeutic agents) are capable of transporting the agents across the BBB or into particular cell types. These compounds are therefore particularly useful in the treatment of neurological diseases.
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申请公布号 |
US2012141416(A1) |
申请公布日期 |
2012.06.07 |
申请号 |
US201013382069 |
申请日期 |
2010.06.30 |
申请人 |
DEMEULE MICHEL;CHE CHRISTIAN;THIOT CARINE;ANGIOCHEM INC. |
发明人 |
DEMEULE MICHEL;CHE CHRISTIAN;THIOT CARINE |
分类号 |
A61K47/48;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/12;A61P13/12;A61P25/00;A61P25/18;A61P25/28;A61P29/00;A61P35/00;C07K14/435;C07K17/14;C07K19/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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