发明名称 |
METHOD FOR TREATMENT OF CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME |
摘要 |
The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome. |
申请公布号 |
US2012128797(A1) |
申请公布日期 |
2012.05.24 |
申请号 |
US201113271624 |
申请日期 |
2011.10.12 |
申请人 |
QUART BARRY D.;ROSENBAUM DAVID P.;NAPO PHARMACEUTICALS, INC. |
发明人 |
QUART BARRY D.;ROSENBAUM DAVID P. |
分类号 |
A61K36/185;A61K31/352;A61K36/47;A61P1/00;A61P1/10;A61P1/12 |
主分类号 |
A61K36/185 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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