发明名称 |
GENERATION OF INDUCED PLURIPOTENT STEM CELLS FROM SMALL VOLUMES OF PERIPHERAL BLOOD |
摘要 |
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from peripheral blood cells, such as human blood progenitor cells, using episomal reprogramming and feeder-free or xeno-free conditions. In certain embodiments, the invention provides novel methods for improving overall reprogramming efficiency with low number of blood progenitor cells. |
申请公布号 |
WO2011159684(A3) |
申请公布日期 |
2012.04.19 |
申请号 |
WO2011US40323 |
申请日期 |
2011.06.14 |
申请人 |
CELLULAR DYNAMICS INTERNATIONAL, INC.;MACK, AMANDA |
发明人 |
MACK, AMANDA |
分类号 |
C12N5/0789;C07K14/475;C12N5/02;C12N5/074 |
主分类号 |
C12N5/0789 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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