| 发明名称 |
Gamma-1 and gamma-3 anti-human cd23 monoclonal antibodies and use thereof as therapeutics |
| 摘要 |
Anti-human CD23 monoclonal antibodies containing human gamma 1 constant domains and therapeutic uses are provided. These antibodies inhibit IL-4 induced IgE production by B-cells significantly greater than antibodies containing other constant domains. |
| 申请公布号 |
ZA9801434(B) |
申请公布日期 |
1998.08.24 |
| 申请号 |
ZA19980001434 |
申请日期 |
1998.02.20 |
| 申请人 |
IDEC PHARMACEUTICALS CORPORATION;SEIKAGAKU CORPORATION |
发明人 |
MITCHELL E. REFF;WILLIAMS S. KLOETZER;TAKEHIKO NAKAMURA |
| 分类号 |
C12N15/02;A61K38/00;A61K39/395;A61P29/00;A61P37/02;A61P37/08;A61P43/00;C07K16/28;C12P21/08 |
主分类号 |
C12N15/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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