发明名称 |
DETOXIFIED ESCHERICHIA COLI IMMUNOGENS. |
摘要 |
Detoxified variants of the pathogenic E. coli 'AcfD precursor' (orf3526) have been identified that raise a substantially similar immune response in a subject as the native AcfD (orB526) protein. The detoxified variants may be further modified to have increased solubility as compared to the native AcfD (orf3526) protein. |
申请公布号 |
MX2012000734(A) |
申请公布日期 |
2012.01.27 |
申请号 |
MX20120000734 |
申请日期 |
2010.07.16 |
申请人 |
NOVARTIS AG |
发明人 |
LAURA SERINO;MARIA RITA FONTANA;DANILO GOMES MORIEL |
分类号 |
C07K14/245;A61K39/02;C12N15/31 |
主分类号 |
C07K14/245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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