摘要 |
Disclosed are triaza-benzocycloheptene compounds represented by general formula (I) wherein R3 is benzene or naphthalene. Processes for preparing the compounds are also disclosed. Also disclosed is the use of the compounds of formula (I) for treating Alzheimer's disease, Parkinson's disease, tauopathies, vascular dementia; acute stroke, traumatic injuries; cerebrovascular accidents, brain cord trauma, spinal cord trauma; peripheral neuropathies, retinopathies, glaucoma, non-insulin dependent diabetes; obesity; manic depressive illness; schizophrenia; alopecia; cancers; parenchymal renal diseases, muscle atrophy, malaria, Pemphigus vulgaris, bone diseases or diseases caused by abnormal GSK3-beta activity.
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申请人 |
SANOFI-AVENTIS;MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
FAYOL, AUDE;LOCHEAD, ALISTAIR;SAADY, MOURAD;VACHE, JULIEN;YAICHE, PHILIPPE |