发明名称 |
CONCENTRATION OF VACCINE ANTIGENS WITH LYOPHILIZATION |
摘要 |
<p>A process for preparing a lyophilised vaccine antigen, comprising steps of (i) increasing the concentration of an antigen in a liquid composition including that antigen using centrifugal filtration and/or ultrafiltration, to provide a concentrated antigen, and (it) lyophilising the concentrated antigen, to provide the lyophilised vaccine antigen. The lyophilised material can be reconstituted and used for vaccine formulation. The process is particularly useful with influenza vaccine antigens.</p> |
申请公布号 |
CA2801151(A1) |
申请公布日期 |
2011.12.08 |
申请号 |
CA20112801151 |
申请日期 |
2011.06.01 |
申请人 |
NOVARTIS AG |
发明人 |
KOMMAREDDY, SUSHMA;SCAMPINI, AMANDA;BAUDNER, BARBARA;O'HAGAN, DEREK;SINGH, MANMOHAN |
分类号 |
A61K39/145 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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