<p>The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.</p>
申请公布号
EP2377873(A1)
申请公布日期
2011.10.19
申请号
EP20110004573
申请日期
2005.09.26
申请人
ALNYLAM PHARMACEUTICALS, INC.
发明人
SOUTSCHEK, JUERGEN;VORNLOCHER, HANS-PETER;HADWIGER, PHILIPP;ELBASHIR, SAYDA
