发明名称 CRYSTALLINE SALT FORMS OF QUINOLINONE-CARBOXAMIDES, SOLVATES THEREOF, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USES THEREOF
摘要 The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.
申请公布号 IL186023(A) 申请公布日期 2011.09.27
申请号 IL20070186023 申请日期 2007.09.18
申请人 THERAVANCE, INC. 发明人
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