| 发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF HUNTINGTON'S DISEASE |
| 摘要 |
Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.
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| 申请公布号 |
US2011213010(A1) |
申请公布日期 |
2011.09.01 |
| 申请号 |
US20090991883 |
申请日期 |
2009.05.08 |
| 申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HAYDEN MICHAEL;CARROLL JEFFREY;WARBY SIMON |
| 分类号 |
A61K31/7088;A61P25/28;C12N5/071;C12Q1/68 |
主分类号 |
A61K31/7088 |
| 代理机构 |
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