发明名称 Isolated organ perfusion combination therapy of cancer
摘要 The invention relates to a combination therapy for the treatment of tumors and tumor metastases comprising administration of integrin ligands, preferably integrin antagonists, together with co-therapeutic agents or therapy forms that have synergistic efficacy when administered together with said ligands, such as chemotherapeutic agents and/or radiation therapy, in isolated organ perfusion. The therapy results in a synergistic potential increase of the inhibition effect of each individual therapeutic on tumor cell proliferation, yielding more effective treatment than found by administering an individual component alone.
申请公布号 US2011165150(A1) 申请公布日期 2011.07.07
申请号 US20060161465 申请日期 2006.01.18
申请人 MERCK PATENT GMBH 发明人 GOODMAN SIMON;GRELL MATTHIAS;TEN HAGEN TIMO L.M.;EGGERMONT ALEXANDER M.M.
分类号 A61K39/395;A61K33/24;A61K38/00;A61K38/08;A61P35/00 主分类号 A61K39/395
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