发明名称 |
TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS. |
摘要 |
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup> and R<sup>5</sup> are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed. |
申请公布号 |
MX2010014002(A) |
申请公布日期 |
2011.02.15 |
申请号 |
MX20100014002 |
申请日期 |
2009.06.19 |
申请人 |
GENENTECH, INC. |
发明人 |
PASTOR, RICHARD;SIU, MICHAEL;ZHU, BING-YAN;MAGNUSON, STEVEN, R.;HAIYING, HE;YISONG, XIAO;JIFU, ZHENG;XING, XU;JUNPING, ZHAO;LIU, WENDY |
分类号 |
A01N43/64;A61K31/41 |
主分类号 |
A01N43/64 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|